Finally I got why my mouse pointer everytime get stuck whenever I start typing or press any key. First I thought it's a bug but today I again verified my mouse setting and found there is a option "Disable touchpad while typing", it is a new gnome-shell feature which wasn't there in gnome-2. I checked this option long back and I thought it only apply when I start any text-editor not in general but if nothing is opened and I press any key then also mouse pointer get stuck. Well now I disabled it and mouse pointer working smoothly.
